Basic Science Researchers

Geoffrey Abrams, MD

Associate Professor of Orthopaedic Surgery

Dr. Abrams' research is focused on elucidating the pathobiology behind tendinoapthy and developing new treatment modalities for the disease. Specifically, his team is studying the role of micro-RNA as it relates to chronic inflammation and stem cell differentiation in the development and perpetuation of chronic tendinopathy.

D. Amanatullah, MD, PhD

Associate Professor of Orthopedic Surgery

Nidhi Bhutani, PhD

Associate Professor of Orthopaedic Surgery

The long-term goal of our research is to understand the fundamental mechanisms that govern and reprogram cellular fate during development, regeneration and disease. We are specifically interested in reprogramming approaches for musculoskeletal regeneration, mechanisms underlying stem cell self-renewal, differentiation and cancer, and epigenetic regulation in development and disease.

Constance Chu, MD

Professor of Orthopaedic Surgery 

My research program brings the best science in cell biology, regenerative medicine, mechanics, and imaging together to restore and rejuvenate damaged joints so that people can live full and healthy lives free of joint pain. Through nearly two decades of research funded by the National Institutes of Health, the Veterans Administration, and the Department of Defense, I have led development of new MRI color mapping techniques and refined new blood testing methods to identify joint aging before OA even starts. 

Stuart Goodman, MD, PhD

The Robert L. and Mary Ellenburg Professor of Surgery and Professor, By Courtesy, of Bioengineering

Our research seeks to understand the mechanisms of various musculoskeletal conditions related to fractures and bone defects, total joint replacement, arthritis, and osteonecrosis etc. based on the cross-talk between cells in the mesenchymal and the hematopoietic lineages. In particular, the key role that macrophages play in the recruitment and differentiation of mesenchymal stem cells (MSCs) during bone regeneration has been brought to focus. 

Jessica Rose, PhD

Professor of Orthopaedic Surgery at the Lucile Salter Packard Children's Hospital and the Stanford University Medical Center

Dr. Rose directs the Motion & Gait Analysis Lab at Lucile Packard Children's Hospital, a multidisciplinary diagnostic service for patients with gait and upper limb movement disorders. Dr. Rose's research investigates early brain and motor development in preterm children and the neuromuscular mechanisms underlying motor deficits in children with cerebral palsy (CP).

Seth Sherman, MD

Associate Professor of Orthopaedic Surgery 

My research focuses on ways to augment tissue healing, improve human performance, and prevent musculoskeletal injuries. Approaching these challenges through parallel basic science and clinical pathways, our team works from the “bedside to the bench and back to the bedside”, identifying areas of clinical need to deliver evidence-based solutions for patients.

Robert L. Smith, PhD

Professor (Research) of Orthopedic Surgery, Emeritus

Fan Yang, PhD

Associate Professor of Orthopaedic Surgery and of Bioengineering

Our research focuses on the fundamental - understand how microenvironmental cues regulate stem cell fate, technological - develop controlled delivery system to direct stem cell differentiation in situ, and translational - stem cells for targeting and delivery of therapeutic factors.

Yunzhi Peter Yang, PhD

Associate Professor of Orthopaedic Surgery and, by courtesy, of Materials Science and Engineering and of Bioengineering

We aim to improve understanding of tissue-like chemistry and structure of medical device design using advanced 3D printing, how these lead to tissue-like properties and functions, and the extent to which they can enhance clinical outcomes. Our research methodology includes concept design and development of medical devices and advanced 3D printing, characterization and evaluation in vitro, and in vivo validation of novel biomaterials and implant devices. 

Jeffrey Yao, MD

Professor of Orthopedic Surgery